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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63166L | (S, R)-LSN 3318839 | (S, R)-LSN 3318839(Isomer-2764704-18-7) | Glucagon Receptor |
(S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in animal models alone or in combination with sitagliptin. | |||
TP2127 | R18 | ||
Antagonist of 14.3.3 proteins (KD ≈80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzy... | |||
T4295 | (R)-GNE-140 | GNE-140 | Dehydrogenase |
(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer. | |||
T35466 | (±)18-HEPE | ||
(±)18-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 18(S)-HEPE and 18(R)-HEPE. Specific biological activity attributed to (±)18-HEPE has not been documented. | |||
T35467 | (±)18-HETE | ||
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasod... | |||
T61402 | PGN36 | ||
PGN36 (Compound 18) is a potent and highly selective antagonist of the cannabinoid CB 2 receptor (CB 2 R). It exhibits exceptional affinity for CB 2 R, with a Ki value of 0.09 μM [1]. | |||
T79988 | Cytochalasin R | ||
Cytochalasin R (compound 17), an analogue of cytochalasin, is derived from the endophytic fungus Phomopsis sp. xz-18 and exhibits potential antifungal activity [1]. | |||
T66698 | (R)-Boc-3-(trifluoromethyl)-β-Phe-OH | ||
(R)-Boc-3-(trifluoromethyl)-β-Phe-OH is a useful organic compound for research related to life sciences. The catalog number is T66698 and the CAS number is 501015-18-5. | |||
T83043 | Anti-MI/R injury agent 1 | ||
Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R) injury. It improves cell viability in cardiomyocytes subjec... | |||
T66773 | (R)-2,5-Ddioxopyrrolidin-1-yl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate | ||
(R)-2,5-Ddioxopyrrolidin-1-yl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate is a useful organic compound for research related to life sciences. The catalog number is T66773 and the CAS number is 3674-18-8. | |||
T36043 | 17(R)-Protectin D1 | 17(R)-Protectin D1 | |
17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when ... | |||
T35494 | (±)11(12)-EET | ||
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms C... | |||
T36215 | 17R(18S)-EpETE | ||
17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium curren... | |||
T35624 | Ajoene | ||
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =... | |||
T37690 | Phenylpyropene A | ||
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).... | |||
T35881 | Resolvin E2 | ||
Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-... | |||
T36679 | Rp-cAMPS sodium salt | ||
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b... |